Pain & Inflammation Relief

• Review: How Red and Near-Infrared Light Reduces Pain
  
  This narrative review explains the mechanisms by which red and near-infrared light (including 660 nm) reduces pain, from calming over-active nerve fibres to lowering inflammatory chemicals, and summarises evidence across musculoskeletal and neuropathic pain conditions.

• Review: The Anti-Inflammatory Effects of Red and NIR Light
  
  This review of red and near-infrared light therapy (660 and 810 nm feature among the studies) describes reduced inflammatory cytokines, prostaglandins and reactive nitrogen species across animal models, and a shift of immune macrophages toward a healing profile, concluding that "one of the most reproducible effects of PBM is an overall reduction in inflammation".

• Review: Laser Light in Inflammatory and Musculoskeletal Disease
  
  This 2019 review (Curr Allergy Asthma Rep) of laser studies (660-940 nm) reports a pooled effect size of 0.85 for pain relief in musculoskeletal disorders and reduced NF-kB, TNF-alpha and IL-1 beta, but notes that 660 nm gave mixed results in arthritis models and that variable protocols limit firm conclusions.

• Meta-Analysis: Red and NIR Light Plus Exercise Reduces Tendon Pain
  
  A systematic review and meta-analysis of 17 randomised trials (835 people) found that red/near-infrared light therapy combined with exercise reduced tendinopathy pain more than sham light plus exercise (about 1 point more on a 10-point scale); light therapy alone was similar to other treatments, and evidence quality ranged from very low to moderate.

• Review: Light Therapy for Arthritis Inflammation
  
  This 2023 review of cell, animal and clinical studies (660-940 nm lasers and LEDs) reports that light therapy lowers TNF-alpha, IL-1 beta and IL-6, suppresses cartilage-degrading enzymes and, at 660 nm, shifts macrophages from the inflammatory M1 type to the reparative M2 type in arthritis models; the authors stress that results depend heavily on dose.

• 660 nm LED Helps with Nerve Pain
  
  In nerve-damaged rats, 660 nm light improved movement and lowered pain by boosting antioxidants and reducing hypersensitivity.

• 660 nm LED Provides Rapid Pain Relief
  
  Mice with acute inflammation experienced fast pain reduction with 660 nm LED light, supporting its use for immediate pain management.
  

HeroSeries panels, HeroBelt and HeroHat use 660nm red light

• 830 nm LED Reduces Pain and Swelling After Eyelid Surgery
  
  In 145 people recovering from blepharoplasty (eyelid surgery), those given 830 nm LED therapy (73 patients) had significantly less swelling, pain and anxiety and faster wound healing than the 72 given standard care, with no adverse effects.

• 830 nm LED Halves Recovery Time in Injured Athletes
  
  In a pilot study of 65 university athletes with 395 sports injuries, an average of 4.3 sessions of 830 nm LED therapy reduced pain by about 6 points on a 10-point scale and cut time to return to play to 9.6 days, versus 19.2 days expected (p=0.0066).

• 830 nm Laser Improves Immune Markers After Wisdom Tooth Surgery
  
  In a placebo-controlled study of 213 wisdom-tooth extractions, 830 nm diode laser treatment changed salivary immune markers (secretory IgA fell from about 547 to 305 mg/L) and thermographic readings, suggesting a calmer post-surgical immune response. Pain scores are not reported in the abstract. Laser study.

• 830 nm Laser Relieves Tennis and Golfer's Elbow in 324 Patients
  
  In a multicentre, double-blind, placebo-controlled study of 324 people with medial or lateral epicondylitis, 830 nm diode laser (with a 632.8/904 nm scanner) achieved total pain relief and restored function in 82% of acute and 66% of chronic cases. While this study used lasers, other studies show "LED light can be as effective as LASER, since both have similar biological effects, with no significant difference between them".

HeroSeries panels and face masks use 830nm NIR light