Neural Function, Depression and Brain Diseases

• Self-administered 810 nm LED treatment changed brain structure and function in a concussion case
  
  In a single case report, a 23-year-old professional hockey player with multiple past concussions used an 810 nm LED device (transcranial plus intranasal) at home for 8 weeks. Follow-up MRI showed increased brain volumes, improved functional connectivity and cerebral blood flow, alongside better neuropsychological test scores. The authors stress that this is one person and that replication studies are needed.

• Whole-head 810 nm near-infrared therapy in Alzheimer's disease: a pilot study
  
  In a small open-label pilot, nine people with Alzheimer's completed four months of whole-head 810 nm NIR treatment (100 mW/cm², 30 minutes, six sessions a week). Mini-Mental State scores rose by an average of 3.2 points and ADAS-cog scores improved by 5 points, with gains still present two months later and no device-related side effects. There was no placebo group, so larger controlled trials are needed.

• 810 nm (and 660 nm) LED light protected neurons from amyloid-beta toxicity in a lab model of Alzheimer's
  
  In a lab study on differentiated neural cells exposed to amyloid-beta, daily LED treatment at 660 nm and 810 nm (3 J/cm², seven days) reduced cell damage, preserved neuron structure and restored acetylcholine levels, suggesting a protective effect on the memory-related cholinergic system. Cell study only.

• Significant Cognition Improvement in Dementia with 810 nm PBM
  
  In a case series of mild to moderate dementia patients, 810 nm pulsed LED therapy led to notable gains in thinking, memory, and daily function, with no side effects.

• Three Doses of 810 nm Laser for Anxiety and Depression in Mice
  
  Different doses of 810 nm NIR light reduced anxiety and depressive behaviors in stressed mice by boosting serotonin and lowering brain stress markers. While this study used lasers, other studies show "LED light can be as effective as LASER, since both have similar biological effects, with no significant difference between them".

• Transcranial PBM for Opioid Use Disorder and Depression
  
  In patients with opioid addiction, 810 nm PBM reduced cravings and depressive symptoms, offering a non-invasive way to support mental health in brain-related disorders.
  

All HeroSeries panels use 810nm NIR light

• Systematic review: transcranial PBM (633-1064 nm, including 850 nm) in chronic traumatic brain injury
  
  A 2024 systematic review of 16 studies (12 case reports/series and 4 clinical studies) of transcranial light therapy for chronic TBI found consistent reports of improved cognition, mood, sleep and cerebral blood flow across wavelengths of 633-1064 nm including 850 nm, but notes small samples and a lack of randomised controlled trials.

• 850 nm LED (Combined with 670 nm) Shows Potential for Parkinson's Disease Treatment
  
  This review of studies highlights that LED therapy at 670 nm and 850 nm directed transcranially or remotely improved motor symptoms like gait and balance, non-motor symptoms such as cognition and smell, and provided neuroprotection by reducing neuronal death and inflammation in Parkinson's animal models and human trials.

• 660/850 nm LED helmet improved fine motor skills in para-athletes
  
  Six boccia para-athletes used a 204-diode helmet emitting 660 and 850 nm (9 J/cm², 15 minutes, three times a week) in a two-week placebo-controlled crossover. Manual dexterity and coordination improved with active treatment but not placebo. Tiny sample; participants were para-athletes, not a Parkinson's population.

• Whole-body 660/850 nm LED bed (or 1070 nm helmet) improved long-COVID brain fog
  
  In an open-label pilot, 14 people with post-COVID brain fog were split between a 1070 nm transcranial helmet and a 660/850 nm whole-body LED bed for 12 sessions over four weeks. Both groups improved significantly on cognitive tests (including MoCA) and EEG measures. Only seven people per group and no sham arm. (Multi-wavelength)

• Home-made 670/810/850 nm LED "bucket" helmets in Parkinson's: early observations
  
  Six people with Parkinson's used home-built LED helmets (670, 810 and 850 nm; one used a 660 nm intranasal device) for up to 24 months. By patient, spouse and physician assessment, about 55% of tracked symptoms improved, 43% were unchanged and 2% worsened, covering both motor and non-motor symptoms. Uncontrolled observational report.

HeroSeries panels, HeroBelt and HeroHat use 850nm NIR light